TY  - JOUR
PY  - 2019//
TI  - A prospective study of psychological distress after prostate cancer surgery
JO  - Psycho-oncology
A1  - Occhipinti, Stefano
A1  - Zajdlewicz, Leah
A1  - Coughlin, Geoffrey D.
A1  - Yaxley, John W.
A1  - Dunglison, Nigel
A1  - Gardiner, Robert A.
A1  - Chambers, Suzanne K.
SP  - 2389
EP  - 2395
VL  - 28
IS  - 12
N2  - BACKGROUND: Men treated for prostate cancer experience heightened psychological distress and have an increased risk of suicide. Management of this distress and risk is crucial for quality urological care.  OBJECTIVE: To identify risk indicators for poorer trajectories of psychological adjustment and health-related quality of life (QoL) after surgery for localised prostate cancer.  DESIGN, SETTING, AND PARTICIPANTS: Patients were newly diagnosed with localised prostate cancer scheduled for surgical treatment. Patients were assessed at baseline (pre-surgery) and 6 weeks, 3 months, 6 months, 12 months, and 24 months post-surgery.  MEASUREMENTS: Assessment measures included sociodemographics, domain-specific and health-related QoL, and psychological distress. Mixed effects regression models were used to analyse the data.  RESULTS AND LIMITATIONS: A total of 233 patients provided data for this analysis (Mage = 60 years, standard deviation [SD] = 4.02; MPSA = 7.37 ng/mL). At baseline, the prevalence of high psychological distress was 28% reducing to 21% at 24 months. Before treatment, younger age, more comorbidities, and worse bowel function were related to greater psychological distress; and younger age and better urinary, sexual, and bowel function were related to better health-related QoL. By contrast, for changes over time, only bowel function was important with better bowel function predicting decreasing psychological distress for men.  CONCLUSIONS: Regular distress screening is indicated over the 24 months after surgery for localised prostate cancer. Care pathways for men with prostate cancer need also to respond to age-specific concerns and health problems associated with comorbidities in aging men. Focussed symptom control for bowel bother should be a priority.<p /> <p>Language: en</p>
LA  - en
SN  - 1057-9249
UR  - http://dx.doi.org/10.1002/pon.5263
ID  - ref1
ER  -