TY  - JOUR
PY  - 2019//
TI  - Association of History of Injection Drug Use with External Cause-Related Mortality Among Persons Linked to HIV Care in an Urban Clinic, 2001-2015
JO  - AIDS and behavior
A1  - Singh, Kanal
A1  - Chander, Geetanjali
A1  - Lau, Bryan
A1  - Edwards, Jessie K.
A1  - Moore, Richard D.
A1  - Lesko, Catherine R.
SP  - 3286
EP  - 3293
VL  - 23
IS  - 12
N2  - High mortality rates among persons with HIV with a history of injection drug use (PWID) are thought to be driven in part by higher rates of external cause-related mortality. We followed 4796 persons aged 18-70 engaged in continuity HIV care from 2001 to 2015 until death or administrative censoring. We compared cause-specific (csHR) and subdistribution hazards (sdHR) of death due to external causes among PWID and persons who acquired their HIV infection through other routes (non-IDU). We standardized estimates on age, sex, race, and HIV-related health status. The standardized csHR for external cause-related death was 3.57 (95% CI 2.39, 5.33), and the sdHR was 3.14 (95% CI 2.16, 4.55). The majority of external cause-related deaths were overdose-related and standardized sdHR was 4.02 (95% CI 2.40, 6.72). Absolute rate of suicide was low but the csHR for PWID compared to non-IDU was most elevated for suicide (6.50, 95% CI 1.51, 28.03). HIV-infected PWID are at a disproportionately increased risk of death due to external causes, particularly overdose and suicide.<p /> <p>Language: en</p>
LA  - en
SN  - 1090-7165
UR  - http://dx.doi.org/10.1007/s10461-019-02497-6
ID  - ref1
ER  -