TY  - JOUR
PY  - 2019//
TI  - The impact of attention deficit hyperactivity disorder in obsessive-compulsive disorder subjects
JO  - Depression and anxiety
A1  - Blanco-Vieira, Thiago
A1  - Santos, Matheus
A1  - Ferrão, Ygor A.
A1  - Torres, Albina R.
A1  - Miguel, Eurípedes C.
A1  - Bloch, Michael H.
A1  - Leckman, James F.
A1  - do Rosário, Maria C.
SP  - 533
EP  - 542
VL  - 36
IS  - 6
N2  - BACKGROUND: Recent findings suggest an association between attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD). Thus, we evaluated the clinical associated features of ADHD in a large sample of adult OCD patients.  METHODS: A cross-sectional study including 955 adult patients with OCD from the Brazilian Research Consortium of Obsessive-Compulsive Spectrum Disorders (C-TOC). Clinical characteristics in adult OCD patients with and without comorbid ADHD were compared using Fisher's exact test, t-tests or Mann-Whitney tests. Bivariate analyses were followed by logistic regression analysis to identify clinical characteristics independently associated with ADHD comorbidity.  RESULTS: The lifetime prevalence of ADHD in adult OCD patients was 13.7%. The current results indicate that OCD + ADHD patients were more severe, had an earlier onset of the obsessive-compulsive symptoms, a higher history of rheumatic fever, with higher frequencies of sensory phenomena and comorbidity with Tourette syndrome. They also had an increased risk for academic impairment and suicide attempts.  CONCLUSION: Adult OCD patients with ADHD present some specific clinical features and may represent a special subgroup of adult OCD. Future studies should focus on the development of interventions more tailored to the phenotype of this subgroup of patients.<p /> <p>Language: en</p>
LA  - en
SN  - 1091-4269
UR  - http://dx.doi.org/10.1002/da.22898
ID  - ref1
ER  -