TY - JOUR PY - 2024// TI - Relationships between trauma types and psychotic symptoms: a network analysis of patients with psychotic disorders in a large, multi-country study in East Africa JO - Comprehensive psychiatry A1 - Stevenson, Anne A1 - Misra, Supriya A1 - Girma, Engida A1 - Isvoranu, Adela-Maria A1 - Akena, Dickens A1 - Alemayehu, Melkam A1 - Atwoli, Lukoye A1 - Gelaye, Bizu A1 - Gichuru, Stella A1 - Kariuki, Symon M. A1 - Kwobah, Edith Kamaru A1 - Kyebuzibwa, Joseph A1 - Mwema, Rehema M. A1 - Newman, Carter P. A1 - Newton, Charles R. J. C. A1 - Ongeri, Linnet A1 - Stroud, Rocky E. 2nd A1 - Teferra, Solomon A1 - Koenen, Karestan C. A1 - Seedat, Soraya SP - e152504 EP - e152504 VL - 133 IS - N2 - BACKGROUND: The link between trauma exposure and psychotic disorders is well-established. Further, specific types of trauma may be associated with specific psychotic symptoms. Network analysis is an approach that can advance our understanding of the associations across trauma types and psychotic symptoms.

METHODS: We conducted a network analysis with data from 16,628 adult participants (mean age [standard deviation] = 36.3 years [11.5]; 55.8% males) with psychotic disorders in East Africa recruited between 2018 and 2023. We used the Life Events Checklist and the Mini International Neuropsychiatric Interview to determine whether specific trauma types experienced over the life course and specific psychotic symptoms were connected. We used an Ising model to estimate the network connections and bridge centrality statistics to identify nodes that may influence trauma types and psychotic symptoms.

RESULTS: The trauma type "exposure to a war zone" had the highest bridge strength, betweenness, and closeness. The psychotic symptom "odd or unusual beliefs" had the second highest bridge strength. Exposure to a war zone was directly connected to visual hallucinations, odd or unusual beliefs, passivity phenomena, and disorganized speech. Odd or unusual beliefs were directly connected to transportation accidents, physical assault, war, and witnessing sudden accidental death.

CONCLUSION: Specific trauma types and psychotic symptoms may interact bidirectionally. Screening for psychotic symptoms in patients with war-related trauma and evaluating lifetime trauma in patients with odd or unusual beliefs in clinical care may be considered points of intervention to limit stimulating additional psychotic symptoms and trauma exposure. This work reaffirms the importance of trauma-informed care for patients with psychotic disorders.

Language: en

LA - en SN - 0010-440X UR - http://dx.doi.org/10.1016/j.comppsych.2024.152504 ID - ref1 ER -