TY  - JOUR
PY  - 2024//
TI  - Inter-relationships of insomnia and psychiatric symptoms with suicidal ideation among patients with chronic schizophrenia: a network perspective
JO  - Progress in neuro-psychopharmacology and biological psychiatry
A1  - Peng, Pu
A1  - Wang, Qianjin
A1  - Zhou, Yanan
A1  - Hao, Yuzhu
A1  - Chen, Shubao
A1  - Wu, Qiuxia
A1  - Li, Manyun
A1  - Wang, Yunfei
A1  - Yang, Qian
A1  - Wang, Xin
A1  - Liu, Yueheng
A1  - Ma, Yuejiao
A1  - He, Li
A1  - Liu, Tieqiao
A1  - Zhang, XiangYang
SP  - e110899
EP  - e110899
VL  - 129
IS  - 
N2  - BACKGROUND: Insomnia is common in patients with schizophrenia, which contributes to worsening psychiatric symptoms and suicidality. We aimed to assess the inter-relationships of insomnia and psychopathology with suicidal ideation (SI) among 1407 Chinese patients with chronic schizophrenia via the network approach.   METHOD: We used Positive and Negative Syndrome Scale, Insomnia Severity Index, and Beck Scale for Suicidal Ideation to assess psychiatric symptoms, insomnia, and SI, respectively. Lifetime suicidal attempts (SA) were collected.   RESULTS: (1) The incidence of insomnia, lifetime SI, lifetime SA, and current SI was 13.5% (n = 190), 22.8% (n = 321), 13.5% (n = 190), and 9.7% (n = 136), respectively. (2) Patients with insomnia had worse clinical symptoms and higher suicidal risk. (3) Daytime dysfunction, sleep-related distress, conceptual disorganization, delusions, anxiety, and poor rapport were the core symptoms, while late sleep onset and sleep dissatisfaction emerged as bridge symptoms connecting insomnia and psychopathology. (4) Depressive mood, hallucinations, poor impulse control, guilty feelings, insomnia-related impaired quality of life, and sleep dissatisfaction were directly associated with SI.   CONCLUSION: Our findings called for formal assessment of insomnia in patients with schizophrenia, which should cover both nocturnal and daytime insomnia symptoms. Targeted interventions for key symptoms may help reduce insomnia, psychiatric symptoms, and SI in patients with schizophrenia.<p />  <p>Language: en</p>
LA  - en
SN  - 0278-5846
UR  - http://dx.doi.org/10.1016/j.pnpbp.2023.110899
ID  - ref1
ER  -