TY  - JOUR
PY  - 2024//
TI  - The use of corticosteroid randomisation after significant head injury (CRASH) prognostic model as mortality predictor of traumatic brain injury patients underwent surgery in low-middle income countries
JO  - Anesthesiology research and practice
A1  - Halimi, Radian A.
A1  - Fuadi, Iwan
A1  - Alby, Dionisius
SP  - e5241605
EP  - e5241605
VL  - 2024
IS  - 
N2  - BACKGROUND: Traumatic brain injury (TBI) is a disruption to normal brain functions caused by traumas such as collisions, blows, or penetrating injuries. There are factors affecting patient outcomes that also have a predictive value. Limited data from low-middle income countries showed a high number of poor outcomes in TBI patients. The corticosteroid randomisation after significant head injury (CRASH) prognostic model is a predictive model that uses such factors and is often used in developed countries. The model has an excellent discriminative ability. However, there is still a lack of studies on its use in surgical patients in low-middle income countries. This study aimed to evaluate the CRASH model's validity to predict 14-day mortality of TBI patients who underwent surgery in low-middle income countries. <br><br>METHODS: This retrospective analytical observational study employed total sampling including all TBI patients who underwent surgery with general anesthesia from January to December 2022. Statistical analysis was performed by applying Mann-Whitney and Fisher exact tests, while the model's discriminative ability was determined through the area under the curve (AUC) calculations. <br><br>RESULTS: 112 TBI patients were admitted during the study period, and 74 patients were included. Independent statistical analysis showed that 14-day mortality risk, age, Glasgow Coma Scale score, TBI severity, pupillary response, and major extracranial trauma had a significant individual correlation with patients' actual mortality outcome (p < 0.05). The AUC analysis revealed an excellent mortality prediction (AUC 0.838; CI 95%). <br><br>CONCLUSION: The CRASH prognostic model performs well in predicting the 14-day mortality of TBI patients who underwent surgery in low-middle income countries.<p />  <p>Language: en</p>
LA  - en
SN  - 1687-6962
UR  - http://dx.doi.org/10.1155/2024/5241605
ID  - ref1
ER  -