TY  - JOUR
PY  - 2007//
TI  - Suicidal behaviour and mortality in first-episode psychosis: the OPUS trial
JO  - British journal of psychiatry. Supplement
A1  - Bertelsen, Mette
A1  - Jeppesen, Pia
A1  - Petersen, Lone
A1  - Thorup, Anne
A1  - Øhlenschlaeger, J
A1  - le Quach, Phuong
A1  - Christensen, Torben Ostergaard
A1  - Krarup, G.
A1  - Jørgensen, P
A1  - Nordentoft, Merete
SP  - s140
EP  - 6
VL  - 51
IS  - Suppl
N2  - BACKGROUND: Those with first-episode psychosis are at high-risk of suicide. AIMS: To identify predictive factors for suicidal thoughts, plans and attempts, and to investigate the rate of suicides and other deaths during the 5 years after first diagnosis and initiation of treatment. METHOD: A longitudinal, prospective, 5-year follow-up study of 547 individuals with first-episode schizophrenia spectrum psychosis. Individuals presenting for their first treatment in mental health services in two circumscribed urban areas in Denmark were included in a randomised controlled trial of integrated v. standard treatment. All participants were followed in the Danish Cause of Death Register for 5 years. Suicidal behaviour and clinical and social status were assessed using validated interviews and rating scales at entry, and at 1- and 2-year follow-ups. RESULTS: Sixteen participants died during the follow-up. We found a strong association between suicidal thoughts, plans and previous attempts, depressive and psychotic symptoms and young age, and with suicidal plans and attempts at 1- and 2-year follow-up. CONCLUSIONS: In this first-episode cohort depressive and psychotic symptoms, especially hallucinations, predicted suicidal plans and attempts, and persistent suicidal behaviour and ideation were associated with high risk of attempted suicide.<p />  <p>Language: en</p>
LA  - en
SN  - 0960-5371
UR  - http://dx.doi.org/10.1192/bjp.191.51.s140
ID  - ref1
ER  -