TY - JOUR PY - 2008// TI - Guidelines for the management of paracetamol poisoning in Australia and New Zealand - explanation and elaboration JO - Medical journal of Australia A1 - Buckley, Nicholas A. A1 - Graudins, Andis A1 - Murray, L. A1 - Fountain, John S. A1 - Daly, Frank F. SP - 296 EP - 301 VL - 188 IS - 5 N2 - Paracetamol is involved in a large proportion of accidental paediatric exposures and deliberate self-poisoning cases, although subsequent hepatic failure and death are both uncommon outcomes. The optimal management of most patients with paracetamol overdose is usually straightforward. However, several differing nomograms and varying recommendations regarding potential risk factors for hepatic injury introduce complexity. In order to reconcile management advice with current Australasian clinical toxicology practice, revised guidelines have been developed by a panel of clinical toxicologists consulting to the poisons information centres in Australia and New Zealand using a workshop and consultative process. This article summarises the rationale for the recommendations made in these new guidelines.
Language: en
LA - en SN - 0025-729X UR - http://dx.doi.org/ ID - ref1 ER -