TY - JOUR PY - 2008// TI - Varenicline-induced mixed mood and psychotic episode in a patient with a past history of depression JO - CNS spectrums A1 - Pumariega, A. J. A1 - Nelson, R. A1 - Rotenberg, Larry SP - 511 EP - 514 VL - 13 IS - 6 N2 - Varenicline is a promising agent with demonstrated efficacy in the promotion of smoking cessation. However, from the time of initial trials, it has been associated with significant psychiatric adverse effects. We describe a case where mixed mood and psychotic disturbance developed in an individual with a history of depression and a family history of bipolar disorder. Based on this case, we hypothesize a possible mechanism of action for these adverse effects and preventive measures that could be undertaken in its effective use.
Language: en
LA - en SN - 1092-8529 UR - http://dx.doi.org/ ID - ref1 ER -