TY - JOUR
PY - 2021//
TI - Efficacy and safety of paediatric medicinal cannabis use: a scoping review
JO - Paediatrics and child health (1996)
A1 - Pawliuk, Colleen
A1 - Chau, Briana
A1 - Rassekh, S. Rod
A1 - McKellar, Terri
A1 - Siden, Harold Hal
SP - 228
EP - 233
VL - 26
IS - 4
N2 - INTRODUCTION: The use of medicinal cannabis in the paediatric age group is increasing despite the lack of evidence for its efficacy or safety.
OBJECTIVE: To map the available evidence on the efficacy and safety of medicinal cannabis in children and adolescents.
METHODS: We conducted a scoping review and searched six electronic databases and grey literature. A study was eligible for inclusion when it investigated the efficacy or safety of medicinal cannabis for any condition, more than half of the participants were 0 to 18 years old, and had any study design except single case reports.
RESULTS: We included 36 studies in our final analysis, 32 of which investigated the efficacy or safety of cannabis in treatment-resistant epilepsy. The remaining 4 studies examined patients with cancer, dysautonomia, Epidermolysis Bullosa, and motor disorders.
CONCLUSIONS: There is a lack of evidence on the efficacy and safety of medicinal cannabis in most paediatric conditions.
Language: en
LA - en SN - 1205-7088 UR - http://dx.doi.org/10.1093/pch/pxaa031 ID - ref1 ER -