TY - JOUR PY - 2021// TI - Efficacy and safety of paediatric medicinal cannabis use: a scoping review JO - Paediatrics and child health (1996) A1 - Pawliuk, Colleen A1 - Chau, Briana A1 - Rassekh, S. Rod A1 - McKellar, Terri A1 - Siden, Harold Hal SP - 228 EP - 233 VL - 26 IS - 4 N2 - INTRODUCTION: The use of medicinal cannabis in the paediatric age group is increasing despite the lack of evidence for its efficacy or safety.

OBJECTIVE: To map the available evidence on the efficacy and safety of medicinal cannabis in children and adolescents.

METHODS: We conducted a scoping review and searched six electronic databases and grey literature. A study was eligible for inclusion when it investigated the efficacy or safety of medicinal cannabis for any condition, more than half of the participants were 0 to 18 years old, and had any study design except single case reports.

RESULTS: We included 36 studies in our final analysis, 32 of which investigated the efficacy or safety of cannabis in treatment-resistant epilepsy. The remaining 4 studies examined patients with cancer, dysautonomia, Epidermolysis Bullosa, and motor disorders.

CONCLUSIONS: There is a lack of evidence on the efficacy and safety of medicinal cannabis in most paediatric conditions.

Language: en

LA - en SN - 1205-7088 UR - http://dx.doi.org/10.1093/pch/pxaa031 ID - ref1 ER -