Citation

Ito Y, Teicher MH, Glod CA, Harper D, Magnus E, Gelbard HA. J. Neuropsychiatry Clin. Neurosci. 1993; 5(4): 401-408.

Affiliation

Department of Psychiatry, Harvard Medical School, Boston, Massachusetts.

Copyright

(Copyright © 1993, American Neuropsychiatric Association, Publisher American Psychiatric Publishing)

DOI

unavailable

PMID

8286938

Abstract

This retrospective study examined the association between abuse history and neurological abnormalities in 115 consecutive patients admitted to a child and adolescent psychiatric inpatient unit. Increased electrophysiological abnormalities were found in abused patients compared with non-abused patients (54.4% vs. 26.9%, P = 0.021), predominantly in the left side of the frontal, temporal, or anterior region (P = 0.036). This may support the hypothesis that early abuse alters brain development, particularly limbic structures. However, a large-scale prospective longitudinal assessment study is needed to interpret this association. Possible clinical consequences of relatively preserved right frontal function are discussed.

Language: en