Citation

Turenne SD, Miles C, Parker LA, Siegel S. Pharmacol. Biochem. Behav. 1996; 53(3): 511-516.

Affiliation

Department of Psychology, Wilfrid Laurier University, Waterloo, Ontario, Canada.

Copyright

(Copyright © 1996, Elsevier Publishing)

DOI

unavailable

PMID

8866948

Abstract

The ability of individual differences in the strength of conditioned taste avoidance (CTA) to predict strength of place conditioning produced by the same drug was assessed. In Phase 1, rats were assigned to High CTA and Low CTA groups on the basis of their intake of saccharin solution previously paired with morphine, amphetamine, lithium, or fenfluramine. In Phase 2, the rats received place conditioning training with the same drug used during Phase 1. The rats that displayed the strongest amphetamine-induced CTA also displayed the strongest amphetamine-induced place preference, suggesting that a common mechanism mediates both effects. On the other hand, the strength of the CTA was unrelated to the strength of the place preference or place aversion produced by morphine, lithium, or fenfluramine.

Language: en