Citation

Dukas LC, Schacht E. J. Rheumatol. Suppl. 2005; 76: 44-46.

Affiliation

Acute Geriatric University Clinic, Kantonsspital, and Ambulatorium Wiesendamm, Basel, Switzerland.

Copyright

(Copyright © 2005, Journal of Rheumatology Publishing)

DOI

unavailable

PMID

16142851

Abstract

Low D-hormone syndrome, a disorder related to low creatinine clearance (CrCl), is associated with a roughly 4-fold increase in risk for falls. Known conditions leading to low D-hormone syndrome are CrCl < 65 ml/min, drug interactions, and chronic inflammatory diseases. This article reviews recent studies showing that treatment with D-hormone analogs, such as alfacalcidol, can reduce the frequency of falls in patients with low D-hormone syndrome.