Citation

de Kluizenaar Y, Gansevoort RT, Miedema HM, de Jong PE. J. Occup. Environ. Med. 2007; 49(5): 484-492.

Affiliation

TNO (Netherlands Organization for Applied Scientific Research), Delft, the Netherlands. yvonne.dekluizenaar@tno.nl

Copyright

(Copyright © 2007, Lippincott Williams and Wilkins)

DOI

10.1097/JOM.0b013e318058a9ff

PMID

17495691

Abstract

OBJECTIVE: The purpose of this study was to assess the relationship between road traffic noise exposure at home and the prevalence of hypertension. METHODS: We conducted cross-sectional analyses in a large random sample (N=40,856) of inhabitants of Groningen City, and in a subsample (the Prevention of Renal and Vascular End-Stage Disease [PREVEND]) study cohort; N=8592). RESULTS: Before adjustment for confounders, road traffic noise exposure was associated with self-reported use of antihypertensive medication in the city of Groningen sample (odds ratio [OR]=1.31 per 10-dB increase in Lden). Adjusted odds ratios were significant for the subjects between 45 and 55 years old in the full model when adjusted for PM10 (OR=1.19) and at higher exposure (Lden >55 dB) only (OR=1.21; with adjustment for PM10, OR=1.31). In the PREVEND cohort, the unadjusted odds ratio was 1.35 for hypertension (systolic and diastolic blood pressure >140 and >90 mm Hg, respectively, or use of antihypertensive medication). Again, the adjusted odds ratio was significant for subjects between 45 and 55 years old (OR=1.27; with adjustment for PM10, OR=1.39). CONCLUSIONS: Exposure to road traffic noise may be associated with hypertension in subjects who are between 45 and 55 years old. Associations seemed to be stronger at higher noise levels.

Language: en