Citation

Samuel J, Thomas K, Jeyaseelan L, Peter JV, Cherian AM. J. Assoc. Physicians India 1995; 43(5): 321-323.

Affiliation

Department of Medicine, Christian Medical College & Hospital, Tamil Nadu.

Copyright

(Copyright © 1995, Association of Physicians of India)

DOI

unavailable

PMID

9081959

Abstract

Seventy two patients admitted to the Intensive Care Unit following ingestion of organophosphorus compounds were studied prospectively with two different doses of pralidoxime (PAM). One group received 1 gm immediately after admission and no further PAM and the other group received infusion of PAM, 1 gm 8 hourly for four days (total 12 gms). The incidence of type II paralysis or intermediate syndrome was 47%. We observed a higher incidence in the 4 days of infusion of PAM group (61%) (20 patients) as compared to the single Bolus dose group (39%) (13 patients). Relative risk 1.48 (confidence interval = 0.9-2.4).

Language: en