Citation

Le Q, Chen Y, Wang X, Li Y, Hong J, Xu J. Invest. Ophthalmol. Vis. Sci. 2011; 52(12): 8951-8956.

Affiliation

Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai 200031, China.

Copyright

(Copyright © 2011, Association for Research in Vision and Ophthalmology)

DOI

10.1167/iovs.11-8355

PMID

22003122

Abstract

Purpose:To assess vision-related quality of life in patients with ocular chemical burns by the application of the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25).Methods:87 patients with ocular chemical burns were enrolled in the study from January 1 through May 31, 2010. Apart from the collection of sociodemographic and clinical data, NEI VFQ-25 with an additional appendix question, being translated to Chinese, was administered to all subjects. Main outcome measures were comparison of the NEI VFQ-25 subscale item scores among subgroups and multivariate analysis of the NEI-VFQ-25 subscale scores.Results:55 subjects were bilaterally burnt and the rest were unilaterally injured. The mean age of enrolled subjects was 39.4 ±11.6 years, with the majority being male (98.9%) and worker (77.0%). The mean composite score of all subjects was 40.4±23.8. The composite score and majority subscale scores of binocularly injured patients were significantly lower than those of monocularly injured ones. Further comparisons among groups divided by either clinical severity classification or BCVA produced similar RESULTS: The BCVA of both better-seeing eye and worse-seeing one strongly correlated with the NEI VFQ-25 composite score (ρ=0.664 and 0.498, both P=0.000). Multivariate regression analysis revealed that VFQ-25 composite score correlated significantly with following independent variables: BCVA of better-seeing eye and worse-seeing eye, the injury classification of less severely injured eye, and correct and immediate irrigation after injury as well.Conclusions:Ocular chemical burns have a significant and extensive impact on patients' visual function outcomes and vision-related QOL.

Language: en