Citation

Drezzet J, Kurobe FC, Nobumoto CT, Pedroso D, Blake M, Valenti VE, Vanderlei LC, Adami F, Vanderlei FM, Moraes SD, Vertamatti MA, Reis AO, Rossi RC, Monteiro CB, de Abreu LC. Int. Arch. Med. 2012; 5(1): 8.

Copyright

(Copyright © 2012, Holtzbrinck Springer Nature Publishing Group - BMC)

DOI

10.1186/1755-7682-5-8

PMID

22353179

PMCID

PMC3296577

Abstract

BACKGROUND: Hydatidiform mole (HM) is characterized by abnormal proliferation of human trophoblast with producers functioning tissues of human chorionic gonadotropin. It can evolve with ovarian cysts tecaluteinicos, hypertension of pregnancy or hyperthyroidism. The incidence of HM is variable and its etiology poorly known, associated with nutritional factors, environmental, age, parity, history of HM, oral contraceptives, smoking, consanguinity or defects in germ cells. There is no reference in literature on HM resulting from sexual violence, objective of this report. METHOD: Description of two cases of HM among 1146 patients with pregnancy resulting from sexual violence treated at Hospital Perola Byington, Sao Paulo, from July 1994 to August 2011. RESULTS: The cases affected young, white, unmarried, low educated and low parity women. Sexual violence was perpetrated by known offenders unrelated to the victims, under death threat. Ultrasound and CT of the pelvis showed bulky uterus compatible with HM without myometrial invasion. One case was associated with theca lutein cysts. The two cases were diagnosed in the second trimester of pregnancy and evolved with hyperthyroidism. There was no hypertension, disease recurrence, metastasis or sexually transmitted infection. CONCLUSION: The incidence of HM was 1:573 pregnancies resulting from rape, within the range estimated for Latin American countries. Trophoblastic material can be preserved to identify the violence perpetrator, considering only the paternal HM chromosomes. History of sexual violence should be investigated in cases of HM in the first half of adolescence and women in a vulnerable condition.

Language: en