Citation

Vandam J, Daenens P, Verbeken EK. J. Fire Sci. 1994; 12(5): 411-423.

Copyright

(Copyright © 1994, SAGE Publishing)

DOI

unavailable

PMID

unavailable

Abstract

The acute inhalation toxicity of the thermal decomposition products of Hydraulic fluids type C was assessed in rats. These fluids consist of a MixtUre Of water, ethylene glycol, polyalkylene glycol and some minor additives. Glissosafe(R) 610 was used as a model. Animals were exposed for one hour to atmospheres resulting from spraying the fluid on a plate heated to 500-degrees-C, 600-degrees-C or 700-degrees-C. They were followed for fourteen days after exposure following the prescriptions of the Sixth Report of the Safety and Health Commission of the European Community. Additional tests were done to follow the evolution of histological damage at one, two, three, five and seven days after exposure to the different temperatures. These results were compared with some quantitative data of the major decomposition products. No mortality occurred. Only slight and transient respiratory discomfort was noticed during exposure due to the presence of sensory irritating products. The effects on growth were virtually nil, except for some slight initial retardation during the first day post-exposure. Histological damage was most pronounced at a decomposition temperature of 500-degrees-C. These results correlated with the quantitative data of the sensory irritating components. Out of this thermal decomposition mixture, formaldehyde seems to contribute most to the toxic effects.