Citation

Uno M. Nippon Ganka Gakkai Zasshi 2015; 119(8): 521-526.

Copyright

(Copyright © 2015, Nihon Ganka Gakkai)

DOI

unavailable

PMID

26390577

Abstract

BACKGROUND: Herbicides containing paraquat are widely used and have occasionally been causing ocular damage. The initial ocular injury caused by paraquat tends to worsen within a few days to 1 week. The toxicity of paraquat is based on the oxidative stress induced by reactive oxygen species. CASE: An 82-year-old woman who had been exposed to herbicide containing paraquat in her left eye presented at Koumeikan Eye Clinic 2 days after the incident. Moderate corneal erosion was diagnosed and treated with ordinary medication, but the corneal lesion worsened. After administration of topical 2% rebamipide eye drops, the corneal lesion resolved rapidly.

CONCLUSION: Because of its role as a radical scavenger, rebamipide has great potential for treatment of corneal injuries caused by herbicides such as paraquat.

Language: ja