Citation

Zhang X, Zhang Z, Chen S, Zhao D, Zhang F, Hu Z, Xiao F, Ma X. Exp. Ther. Med. 2015; 10(4): 1293-1296.

Affiliation

Intensive Care Unit, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.

Copyright

(Copyright © 2015, Spandidos Publications)

DOI

10.3892/etm.2015.2664

PMID

26622480

Abstract

Nitrogen mustards are chemical agents that are similar to sulfur mustards, with similar toxicities. The present study describes a case of nitrogen mustard-induced acute respiratory failure and myelosuppression in a 33-year-old man. The patient, who was accidentally exposed to nitrogen mustard hydrochloride in a pharmaceutical factory, exhibited severe inhalation injury and respiratory symptoms. Laboratory tests revealed reduced white blood cell counts and lowered platelet levels during the first 6 days after the skin exposure to nitrogen mustard. Following treatment with mechanical ventilation, immunity-enhancing agents and nutritional supplements for 1 month, the patient successfully recovered and was released from hospital.

Language: en