Citation

Stankovic I, Stefanova E, Tomić A, Lukić MJ, Stojković T, Marković V, Stojmenović GM, Kresojević N, Svetel M, Kostić V. J. Neuropsychiatry Clin. Neurosci. 2016; 28(3): 205-210.

Affiliation

From Neurology Clinic, Clinical Center of Serbia, Belgrade, Serbia (IS, ES, AT, MJL, TS, VM, GMS, NK, MS, VK); and School of Medicine, University of Belgrade, Belgrade, Serbia (ES, MS, VK).

Copyright

(Copyright © 2016, American Neuropsychiatric Association, Publisher American Psychiatric Publishing)

DOI

10.1176/appi.neuropsych.15100244

PMID

26900739

Abstract

Neuropsychiatric symptoms (NPS) are common in Parkinson's disease (PD). The aim of this study was to estimate the correlates of NPS in patients with PD in the initial motor stage of the disease (hemiparkinsonism). A total of 111 patients with PD and 105 healthy control participants were assessed. Patients with PD experienced apathy, depression, and anxiety more frequently compared with healthy controls. Sleep disturbances occurred commonly in early PD patients. Patients with PD and mild cognitive impairment (MCI) had depression and anxiety more frequently, but not apathy, compared with patients with PD without MCI. The results of this study confirm a high burden of NPS even in the earliest motor stage of PD.

Language: en