Citation

Lee R. Curr. Behav. Neurosci. Rep. 2017; 4(2): 151-165.

Affiliation

Associate Professor of Psychiatry and Behavioral Neuroscience, The University of Chicago, Department of Psychiatry and Behavioral Neuroscience, rlee@yoda.bsd.uchicago.edu, 773-834-5673, MC 3077, 5841 S. Maryland Ave, Chicago, IL 60637.

Copyright

(Copyright © 2017, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s40473-017-0116-7

PMID

29399432

PMCID

PMC5793931

Abstract

PURPOSE OF REVIEW: Paranoid Personality Disorder (PPD) has historically been neglected by science out of proportion to its prevalence or its association with negative clinical outcomes. This review provides an update on what is known about PPD regarding its prevalence, demographics, comorbidity, biological mechanism, risk factors, and relationship to psychotic disorders. RECENT FINDINGS: PPD has long been the subject of a rich and prescient theoretical literature which has provided a surprisingly coherent account of the psychological mechanism of non-delusional paranoia. Available data indicate that PPD has a close relationship with childhood trauma and social stress. Descriptive data on a sample of 115 individuals with Paranoid Personality Disorder is examined in comparison with a group of individuals with Borderline Personality Disorder. The descriptive data largely confirm previously identified relationships between Paranoid Personality Disorder and childhood trauma, violence, and race. We identify important similarities to and differences from Borderline Personality Disorder. SUMMARY: PPD continues to be an important construct in the clinic and the laboratory. Available data lead to a reconsideration of the disorder as more closely related to trauma than to schizophrenia.

Language: en

Keywords

Borderline Personality Disorder; Childhood Trauma; Corticotropin-Releasing Hormone; Paranoia; Paranoid Personality Disorder; Personality Disorder