Citation

Costello DM, Kaye AH, O'Brien TJ, Shultz SR. J. Clin. Neurosci. 2018; 56: 1-6.

Affiliation

Department of Medicine, The Royal Melbourne Hospital, The University of Melbourne, VIC 3010, Australia; Departments of Neuroscience and Medicine, Central Clinical School, The Alfred Hospital, Monash University, Melbourne, VIC, 3004, Australia.

Copyright

(Copyright © 2018, Elsevier Publishing)

DOI

10.1016/j.jocn.2018.07.002

PMID

30055944

Abstract

Sport-related concussion is a common form of mild traumatic brain injury that is now recognised as a serious health issue. Growing evidence suggests concussion may result in long-term and severe neurological disabilities. Recent research into the diagnosis and management of concussion may provide new approaches to concussion management that limit the potential long-term adverse effects of concussion. This paper summarises the problem of sport-related concussion and reviews key factors (sex, age, genetics) that may modify concussion outcomes. Current sport-related concussion tools are described. Analysis of emerging methods of acute concussion diagnosis using objective fluid and neuroimaging biomarkers is provided. These new concussion biomarkers have the potential to change management of sport-related concussion.

Copyright © 2018 Elsevier Ltd. All rights reserved.

Language: en

Keywords

Biomarkers; Blood; Chronic traumatic encephalopathy; MRI; Management; Mild traumatic brain injury