Citation

Chen CC, Hsieh PC, Chen CPC, Hsieh YW, Chung CY, Lin KL. J. Clin. Med. 2019; 8(3): e8030390.

Affiliation

Study Group for Prevention and Protection Against Child Abuse and Neglect, Chang Gung Memorial Hospital, 5 Fuhsing St., Taoyuan 333, Taiwan. lincgh@cgmh.org.tw.

Copyright

(Copyright © 2019, MDPI: Multidisciplinary Digital Publishing Institute)

DOI

10.3390/jcm8030390

PMID

30897787

Abstract

Children with abusive head trauma tend to have worse outcomes than children with accidental head trauma. However, current predictors of poor outcomes for children with abusive head trauma are still limited. We aim to use clinical data to identify early predictors of poor outcome at discharge in children with abusive head trauma. In the 10-year observational retrospective cohort study, children aged between zero and four years with abusive or accidental head trauma were recruited. Multivariate logistic regression models were applied to evaluate factors associated with poor prognosis in children with abusive head trauma. The primary outcome was mortality or a Glasgow Coma Scale (GCS) motor component score of less than 6 at discharge. A total of 292 head trauma children were included. Among them, 59 children had abusive head trauma. In comparison to children with accidental head trauma, children with abusive head trauma were younger, had more severe head injuries, and experienced a higher frequency of post-traumatic seizures. Their radiologic findings showed common presence of subdural hemorrhage, cerebral edema, and less epidural hemorrhage. They were more in need of neurosurgical intervention. In the multivariate analysis for predictors of poor outcome in children with abusive head trauma, initial GCS ≤ 5 (versus GCS > 5 with the adjusted odds ratio (OR) = 25.7, 95% confidence interval (CI) = 1.5⁻432.8, p = 0.024) and older age (per year with the adjusted OR = 3.3, 95% CI = 1.2⁻9.5, p = 0.024) were independently associated with poor outcome. These findings demonstrate the characteristic clinical differences between children with abusive and accidental head trauma. Initial GCS ≤ 5 and older age are predictive of poor outcome at discharge in children with abusive head trauma.

Language: en

Keywords

Glasgow Coma Scale; abusive head trauma; accidental head trauma; poor outcome; predictors