Citation

Yöntem A, Aslan N, Horoz ÖÖ, Beyazit AK, Melek E, Yildizdas D. J. Pediatr. Intensive Care 2019; 8(4): 255-258.

Affiliation

Division of Pediatric Intensive Care Unit, Faculty of Medicine, Çukurova University, Adana, Turkey.

Copyright

(Copyright © 2019, Georg Thieme Verlag)

DOI

10.1055/s-0039-1695046

PMID

31673464

PMCID

PMC6821537

Abstract

Metformin is an oral antidiabetic medication which belongs to the class biguanide. Its most hazardous and life-threatening side effect is lactic acidosis which has been increasingly reported in recent years. Early diagnosis and aggressive treatment approaches have significantly reduced morbidity and mortality rates in metformin intoxication. In this case report, we emphasize the importance of early continuous renal replacement therapy in metformin-associated lactic acidosis in a 16-year-old patient who developed severe renal damage during the follow-up period of renal replacement therapy due to lactic acidosis after taking metformin in a suicide attempt.

© Thieme Medical Publishers.

Language: en

Keywords

lactic acidosis; metformin; overdose; renal replacement therapy