SAFETYLIT WEEKLY UPDATE

We compile citations and summaries of about 400 new articles every week.
RSS Feed

HELP: Tutorials | FAQ
CONTACT US: Contact info

Search Results

Journal Article

Citation

Bobholz SA, Brett BL, España LY, Huber DL, Mayer AR, Harezlak J, Broglio SP, McAllister T, McCrea MA, Meier TB, CARE Consortium Investigators. Br. J. Sports Med. 2020; ePub(ePub): ePub.

Copyright

(Copyright © 2020, BMJ Publishing Group)

DOI

10.1136/bjsports-2020-102002

PMID

32917671

Abstract

OBJECTIVES: To determine the acute and early long-term associations of sport-related concussion (SRC) and subcortical and cortical structures in collegiate contact sport athletes.

METHODS: Athletes with a recent SRC (n=99) and matched contact (n=91) and non-contact sport controls (n=95) completed up to four neuroimaging sessions from 24 to 48 hours to 6 months postinjury. Subcortical volumes (amygdala, hippocampus, thalamus and dorsal striatum) and vertex-wise measurements of cortical thickness/volume were computed using FreeSurfer. Linear mixed-effects models examined the acute and longitudinal associations between concussion and structural metrics, controlling for intracranial volume (or mean thickness) and demographic variables (including prior concussions and sport exposure).

RESULTS: There were significant group-dependent changes in amygdala volumes across visits (p=0.041); this effect was driven by a trend for increased amygdala volume at 6 months relative to subacute visits in contact controls, with no differences in athletes with SRC. No differences were observed in any cortical metric (ie, thickness or volume) for primary or secondary analyses.

CONCLUSION: A single SRC had minimal associations with grey matter structure across a 6-month time frame.


Language: en

Keywords

concussion; sport; MRI

NEW SEARCH


All SafetyLit records are available for automatic download to Zotero & Mendeley
Print