Citation

Spielmans GI, Parry P. Psychiatr. Res. Clin. Pract. 2021; 3(2): 97.

Copyright

(Copyright © 2021, American Psychiatric Association Publishing)

DOI

10.1176/appi.prcp.20200038

PMID

36101666

PMCID

PMC9175679

Abstract

In their article "Increases in suicide deaths among adolescents and young adults following US Food and Drug Administration antidepressant boxed warnings and declines in depression care" Lu et al. claimed that the suicidality Black Box Warning for antidepressants led to decreased treatment of depression, which caused a high number of excess suicides among adolescents and young adults in the United States (1).

Treatment of youth depression has actually not substantially decreased since the Black Box warning. Lu et al. found a decrease in antidepressant treatment of less than one percentage point among children and adolescents from 2000 to 2010 (2). Kafali et al. found that antidepressant prescription rates for youth returned to prewarning levels by 2009 (3). Among parents who indicated that their child had severe impairment on the Columbia Impairment Scale, there was no decrease in antidepressant prescriptions after the warning. Valluri et al. examined changes in antidepressant prescribing from 2004 to 2006 and found that adolescents with major depressive disorder did not experience a decrease in antidepressant treatment (4). Rather, decreases in antidepressant prescribing occurred among those with major depression not otherwise specified and dysthymia diagnoses.

Furthermore, Plöderl & Hengartner found a strong correlation between increased self-reported antidepressant use and more self-reported suicide attempts between 2004 and 2016 among adolescents...

Language: en