Citation

Yoshimura R, Yamada Y, Ueda N, Nakamura J. Hum. Psychopharmacol. 2000; 15(5): 357-360.

Copyright

(Copyright © 2000, John Wiley and Sons)

DOI

10.1002/1099-1077(200007)15:5<357::AID-HUP174>3.0.CO;2-K

PMID

unavailable

Abstract

A case of acute lithium intoxication is presented in which plasma levels of 3-methoxy-4-hydroxyphenylglycol (MHPG), 5-hydroxyindoleacetic acid (5-HIAA), and homovanillic acid (HVA) were longitudinally measured during the intoxication period. Plasma levels of MHPG and 5-HIAA, but not HVA were increased during the intoxication period. These results suggest that toxic levels of lithium concentration occurred due to transient enhancement of serotonin and noradrenaline function. Dopamine function was not affected. Copyright (C) 2000 John Wiley and Sons, Ltd.

Language: en

Keywords

3-methoxy-4-hydroxyphenylglycol (MHPG); 4 hydroxy 3 methoxyphenylethylene glycol; 5 hydroxyindoleacetic acid; 5-hydroxyindoleacetic acid (5-HIAA); adult; article; case report; depression; drug intoxication; female; homovanillic acid; Homovanillic acid (HVA); human; lithium; lithium carbonate; Lithium intoxication; noradrenalin; plasma; priority journal; serotonin; suicide attempt