Citation

von Giesen HJ, Backer R, Hefter H, Arendt G. J. Neuropsychiatry Clin. Neurosci. 2001; 13(1): 88-94.

Copyright

(Copyright © 2001, American Neuropsychiatric Association, Publisher American Psychiatric Publishing)

DOI

10.1176/jnp.13.1.88

PMID

11207334

Abstract

The authors examined the effects of depressive mood (Hamilton Rating Scale for Depression [Ham-D]) on basal ganglia-mediated psychomotor speed (motor test battery) in 202 HIV-1 seropositive homosexual males with no prior history of antiretroviral treatment. HIV-1 seropositive patients showed a significant slowing of most rapid alternating movements (MRAM) and significantly prolonged contraction times (CT) compared with 66 HIV-1 seronegative male control subjects. Factor analysis of Ham-D scores isolated a factor containing the items depressed mood, suicide, and psychic and somatic anxiety. This factor did not correlate with MRAM or CT. Depression and psychomotor speed are independent in HIV-1infection.

Language: en

Keywords

Adult; AIDS Dementia Complex; Anxiety Disorders; Depressive Disorder; Diagnosis, Differential; HIV Seropositivity; HIV-1; Humans; Male; Middle Aged; Personality Inventory; Psychomotor Disorders; Reaction Time