Citation

LoVecchio F, Katz K, Watts D, Wood I. J. Med. Toxicol. 2008; 4(3): 149-150.

Affiliation

Banner Good Samaritan Regional Poison Center, Maricopa Medical Center, Department of Emergency Medicine, Phoenix, AZ, USA. Frank.LoVecchio@bannerhealth.com

Copyright

(Copyright © 2008, Holtzbrinck Springer Nature Publishing Group)

DOI

unavailable

PMID

18821486

Abstract

INTRODUCTION: Unintentional methotrexate (MTX) acute oral overdose is rarely reported. METHODS: We conducted a retrospective chart review of all human exposure calls (>150,000 charts) for MTX ingestions reported to our Poison Center during 2000-2003. RESULTS: Thirteen patients met the criteria. The average amount of MTX ingested was 13.03 mg (data from 7 cases), and the average patient age was 43 years (20 months to 80 years). No significant toxicities occurred. DISCUSSION: Although intravenous MTX toxicity can be severe, this does not appear to be a phenomenon associated with either acute unintentional or suicidal oral ingestion.

Language: en