Citation

Zupan LH, Merfeld DM. Exp. Brain Res. 2008; 191(4): 505-511.

Affiliation

Department of Otology and Laryngology, Harvard Medical School, Boston, MA, USA.

Copyright

(Copyright © 2008, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s00221-008-1540-4

PMID

18843487

PMCID

PMC3095945

Abstract

The otolith organs respond equivalently to changes in gravitational force due to head tilt and to changes in inertial force due to linear acceleration. It has been shown that the central nervous system (CNS) uses internal models of the laws of physics to distinguish tilt from translation. Models with these internal models predict that illusory tilt, if large enough, will be accompanied by an illusion of linear motion. To investigate this prediction, we measured interaural, self-motion, direction-detection thresholds in darkness and with roll optokinetic stimulation. Each lateral translation consisted of a single cycle of sinusoidal acceleration, after which subjects indicated whether they translated to the left or right. We found that the interaural direction-detection threshold measured during clockwise and counterclockwise optokinetic stimulation shifted in opposite directions relative to thresholds in darkness. Using a generalized linear model, we determined that this finding was statistically significant (P < 0.005) and is consistent with the prediction that illusory tilt should be accompanied by a non-zero neural estimate of linear velocity that, if large enough (supra-threshold), contributes to translation perception.

Language: en