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Journal Article

Citation

Sandeep Reddy Y, Abbdul Nabi S, Apparao C, Srilatha C, Manjusha Y, Sri Ram Naveen P, Krishna Kishore C, Sridhar A, Siva Kumar V. Ren. Fail. 2012; 34(7): 880-884.

Affiliation

Department of Nephrology, Sri Venkateswara Institute of Medical Sciences , Tirupati , India.

Copyright

(Copyright © 2012, Informa - Taylor and Francis Group)

DOI

10.3109/0886022X.2012.687346

PMID

22680304

Abstract

We studied paraphenylenediamine (PPD)-related acute kidney injury (AKI) in 81 patients and also in albino rats experimentally. In the patients' group AKI was found in 32.7%. Of them, 81.4% needed dialysis support. The overall mortality was 25.9%. In experimental rats the renal lesions were noted in all and they were glomerular congestion, intertubular (interstitial) hemorrhages, acute tubular necrosis, mesangial proliferation, and intratubular casts. The severity of renal injury appears to be dose dependent.


Language: en

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