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Weber ML, Lynall RC, Hoffman NL, Miller EH, Kaminski TW, Buckley TA, Benjamin HJ, Miles CM, Whitlow CT, Lintner L, Broglio SP, McCrea M, McAllister T, Schmidt JD. Ann. Biomed. Eng. 2018; ePub(ePub): ePub.


Concussion Research Laboratory, Department of Kinesiology, University of Georgia, Athens, GA, USA.


(Copyright © 2018, Holtzbrinck Springer Nature Publishing Group)






The purpose of this study was to compare global and specific health-related quality of life (HRQOL) throughout concussion recovery between those with and without concussion history. Student-athletes diagnosed with concussion completed global (Short Form-12v2; SF-12) and specific (Hospital Anxiety and Depression Scale: HADS) HRQOL assessments at baseline, 24-48 h, asymptomatic, return-to-play, and 6-months post-injury. Baseline scores were compared to post-injury time points for SF-12 subscores (physical and mental; PCS-12, MCS-12) and HADS subscores (depression and anxiety; HADS-D, HADS-A). We conducted a 2 × 5 mixed model ANOVA for group (with and without concussion history) and time (four post-injury assessments compared to baseline). We did not observe interaction or main effects for group, except those with concussion history had worse HADS-D subscores than those without concussion history. PCS-12 subscores were worse at 24-48 h, asymptomatic, and return-to-play compared to baseline, but returned to baseline 6-months post-injury. MCS-12 subscores did not differ at any time points. HADS-D subscores worsened 24-48 h post-injury, but improved for additional assessments compared to baseline. HADS-A improved post-injury compared to baseline at asymptomatic, return-to-play, and 6-month assessments, but was similar to baseline 24-48 h post-injury. HRQOL physical aspects slightly worsened post-injury and restored to baseline after returning to play.

Language: en


Hospital anxiety and depression scale; Mild traumatic brain injury; Short-Form 12; Sport-related concussion


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