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Journal Article

Citation

Vodovar D, Langrand J, Tournier N, Mégarbane B. Rev. Med. Interne 2019; 40(6): 389-394.

Vernacular Title

La crise des overdoses américaines : une menace pour la France ?

Affiliation

Fédération de toxicologie FeTox, hôpital Lariboisière/Fernand-Widal, AP-HP, 75010 Paris, France; Inserm UMRS 1144, 4, avenue de l'Observatoire, 75006 Paris, France; Université Paris-Diderot, 75013 Paris, France; Réanimation médicale et toxicologique, hôpital Lariboisière, 2, rue Ambroise-Paré, Paris, France.

Copyright

(Copyright © 2019, Elsevier Publishing)

DOI

10.1016/j.revmed.2018.10.389

PMID

30429046

Abstract

Since the 2000s, a concerning increase in opioid-analgesic-related overdoses and deaths has been reported in the United States. In contrast with opioid overdoses reported in the 80-90s mostly involving heroin, currently it is the misuse of opioid analgesics that is mainly responsible for opioid overdoses. This crisis is related to factors (not limited to the US) which occurred during the 90s and which have led to a broad prescription of opioids in non-cancer pain. In Europe and France, there is (but to a much lesser extent) an increase in strong opioid consumption and in opioid prescription related morbi-mortality. This situation, which can be described as "worrying" today, requires awareness among the French medical community, both upstream (rational prescription of opioids) and downstream (optimal management of opioid poisoning) from the opioid prescription.

Copyright © 2018 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.


Language: fr

Keywords

Dépression respiratoire; Intoxication; Naloxone; Opioid; Opioïdes; Overdose; Poisoning; Respiratory depression

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