Citation

Liotier J, Barbier M, Plantefeve G, Duale C, Deteix P, Souweine B, Coudoré F. Clin. Toxicol. (Phila) 2008; 46(9): 905-907.

Affiliation

Nephrology and Reanimation, Centre Hospitalier Universitaire, Clermont-Ferrand, France.

Copyright

(Copyright © 2008, Informa - Taylor and Francis Group)

DOI

10.1080/15563650802269893

PMID

19003597

Abstract

INTRODUCTION: The clinical signs of acute trichlorethylene overdose are commonly coma, cardiac conduction disturbances, diarrhea, and vomiting. We report a case of intentional massive trichlorethylene ingestion inducing a fatal abdominal compartment syndrome (ACS). CASE REPORT: A 47-year-old woman was admitted to the emergency department after intentionally ingesting 500 mL of trichlorethylene and benzodiazepines. She rapidly developed coma and abdominal distension leading to multiple organ failure. Subsequent surgical evaluation revealed abdominal perforation and necrosis, and life-sustaining treatments were therefore withdrawn. DISCUSSION: This is a primary ACS that can be explained from experimental data on the pathophysiology of pneumatosis cystoides coli. For this case, we discuss multiple etiological factors for intra-abdominal hypertension (IAP), such as paralytic ileus and massive fluid resuscitation due to the direct toxicity of ingested trichlorethylene. CONCLUSION: Patients ingesting trichlorethylene need to be closely evaluated for risk of digestive damage and perforation. Early prompt laparotomy must be performed in cases of ACS.

Language: en