Citation

Zweig-Frank H, Paris J, Ng Ying Kin NM, Schwartz G, Steiger H, Vasavan Nair NP. Psychiatry Res. 2006; 141(3): 337-341.

Affiliation

Department of Psychology, Concordia University, Montreal, Québec, Canada.

Copyright

(Copyright © 2006, Elsevier Publishing)

DOI

10.1016/j.psychres.2005.02.009

PMID

16497388

Abstract

This study examined whether abnormal responses to neurobiological challenge tests in borderline personality disorder (BPD) are related to a history of childhood sexual abuse (CSA). We compared patients meeting BPD criteria (n=24), with and without histories of CSA, with normal controls (n=12) on the results of challenges with meta-chlorphenylpiperazine (m-CPP), pyridostigmine and clonidine. No differences were found between abused and non-abused patients with BPD. These results do not support the hypothesis that CSA is directly related to neurobiological abnormalities in BPD.

Language: en