Citation

Saario I, Linnoila M, Mattila MJ. Br. J. Clin. Pharmacol. 1976; 3(5): 843-848.

Copyright

(Copyright © 1976, John Wiley and Sons)

DOI

unavailable

PMID

973981

PMCID

PMC1428934

Abstract

Forty-five out-patients with clinically manifested anxiety were tested in order to study the effects of 2 weeks' treatment with placebo, diazepam (5-10 mg three times daily) or thioridazine (25-50 mg three times daily) on their psychomotor skills related to driving. When compared with placebo, diazepam increased the number of mistakes in reaction and co-ordination tests and also decreased ability to discriminate the fusion of flickering light. When compared to other groups, reactive and co-ordinative skills were more impaired in patients treated with thioridazine which also impaired divided attention. Aubjectively thioridazine was not experienced as effective an anxiolytic as diazepam.

Language: en