Citation

Oreland L, Wiberg A, Åsberg M, Träskman L, Sjöstrand L, Thorén P, Bertilsson L, Tybring G. Psychiatry Res. 1981; 4(1): 21-29.

Copyright

(Copyright © 1981, Elsevier Publishing)

DOI

unavailable

PMID

6164071

Abstract

Platelet monoamine oxidase (MAO) activity and cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5HIAA), homovanillic acid (HVA), and 4-hydroxy-3-methoxyphenylglycol (HMPG) were simultaneously measured in 20 currently depressed patients, 11 recovered depressed patients, 15 nondepressed suicide attempters, and 42 healthy control subjects. Both 5HIAA and HVA were positively and significantly correlated to platelet MAO activity in the healthy subjects, but not in any of the patient groups. Suicide attempters had significantly lower CSF 5HIAA than nonsuicidal patients.

Language: en