Citation

Wagner A, Aberg-Wistedt A, Åsberg M, Ekqvist B, Mårtensson B, Montero D. Psychiatry Res. 1985; 16(2): 131-139.

Copyright

(Copyright © 1985, Elsevier Publishing)

DOI

unavailable

PMID

3865253

Abstract

3H-Imipramine binding in platelets was measured in 63 severely depressed hospitalized patients, who had been drug free (with the exception of moderate doses of benzodiazepines) for at least 1 month, and in 53 healthy control subjects of comparable age and sex distribution. Bmax of 3H-imipramine binding was significantly lower in the depressed subjects (1012 +/- SD 295 vs. 1123 +/- SD 178 fmole/mg protein). Depressed patients who had attempted suicide by violent means tended to have higher Bmax than nonviolent attempters.

Language: en