Citation

Roy A, Pickar D, De Jong J, Karoum F, Linnoila M. Biol. Psychiatry 1989; 25(3): 341-350.

Affiliation

Laboratory of Clinical Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892.

Copyright

(Copyright © 1989, Elsevier Publishing)

DOI

unavailable

PMID

2914156

Abstract

We examined for relationships between suicidal behavior and noradrenergic function in depression. We compared depressed patients who had or had never attempted suicide and controls on cerebrospinal fluid, plasma, and urinary indices of noradrenergic function. There was no consistent pattern of significant findings in relationship to depressed patients who had attempted suicide. Thus, these essentially negative results suggest that the noradrenergic system is probably not a major determinant of suicidal behavior in depressed patients.

Language: en