Citation

Roy A, Lamparski D, De Jong J, Adinoff B, Ravitz B, George DT, Nutt D, Linnoila M. Acta Psychiatr. Scand. 1990; 81(1): 58-61.

Affiliation

Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland.

Copyright

(Copyright © 1990, John Wiley and Sons)

DOI

unavailable

PMID

1691893

Abstract

Reduced cerebrospinal fluid (CSF) levels of the serotonin metabolite 5-hydroxyindoleacetic acid have been reported to be commonly associated with suicidal behaviour. Alcoholics are known to often manifest suicidal behaviour. Therefore, we compared cerebrospinal fluid levels of monoamine metabolites in alcoholics who had (n = 20) and had not (n = 108) attempted suicide and healthy volunteers (n = 30). There were no significant differences among the 3 groups for CSF levels of either 5-hydroxyindoleacetic acid, the dopamine metabolite homovanillic acid, norepinephrine, or the norepinephrine metabolite 3-methoxy-4-hydroxyphenylglycol.

Language: en