Citation

Ramcharitar V, Levine BS, Goldberger BA, Caplan YH. Forensic Sci. Int. 1992; 56(2): 151-156.

Affiliation

Office of the Chief Medical Examiner, State of Maryland, Baltimore 21201.

Copyright

(Copyright © 1992, Elsevier Publishing)

DOI

unavailable

PMID

1452106

Abstract

A fatality due to the ingestion of bupropion and ethanol is presented. Bupropion and its metabolites were extracted from several tissues and identified using gas chromatography with nitrogenphosphorus and mass spectrometry detection. The concentrations of bupropion, hydroxybupropion and the erythroamino and threoamino alcohol metabolites in heart blood were 4.2, 5.0, 0.6 and 4.6 mg/l, respectively. The heart blood ethanol concentration was 0.27 g/dl. In addition, bupropion was distributed as follows: subclavian blood, 6.2 mg/l; bile, 1.4 mg/l; kidney, 2.4 mg/l; liver, 1.0 mg/kg; stomach contents, 16 mg and urine, 37 mg/l.

Language: en