Citation

Gaines TB. Science 1962; 138(3546): 1260-1261.

Copyright

(Copyright © 1962, American Association for the Advancement of Science)

DOI

unavailable

PMID

13946141

Abstract

Repeated administration of the phenothiazine derivatives chlorpromazine and promazine increased the toxicity of a single dose of parathion in male rats. In female rats, a single dose of 5 mg/kg of promazine increased the toxicity of a single dose of parathion, but had no apparent effect on the toxicity of a single dose of Phosdrin. Repeated dosage with chlorpromazine and atropine, or promazine and atropine, after administration of parathion at the same rate, resulted in a slightly higher mortality in female rats than did atropine or no treatment.

Language: en