Citation

Oberdörster G, White R, Rabin R, Clarkson T, Irons R, Gardner D, Taylor GR, Sonnenfeld G, Thomas R. Fundam. Appl. Toxicol. 1994; 22(2): 161-171.

Affiliation

Department of Environmental Medicine, University of Rochester, New York 14642.

Copyright

(Copyright © 1994, Elsevier Publishing)

DOI

unavailable

PMID

7911766

Abstract

Results of the microbial and immunological studies discussed above clearly illustrate an in-flight or post-flight blunting of the cellular immune mechanism in humans and test animals, coincident with a relative increase in pathogenic microorganisms. This situation predicts an increased incidence of in-flight infectious disease events. To prevent this from occurring, most observers agree that a robust program of preflight and in-flight immunological and microbiological monitoring, combined with an effective countermeasures program, are required for optimally successful long-duration spaceflight.

Language: en