Citation

Zolotokrylina ES. Anesteziol. Reanimatol. 1996; (1): 9-13.

Vernacular Title

Voprosy patogeneza i lecheniia poliorgannoi nedostatochnosti u bol'nykh s

Copyright

(Copyright © 1996, Meditsina)

DOI

unavailable

PMID

8686955

Abstract

Analysis of the results of treatment of 583 patients with grave and terminal stages of shock resultant from severe combined injuries and blood loss, hospitalized in resuscitation wards, showed visceral involvement and development of pyoinflammatory complications in the early postresuscitation period (days 5-10 of treatment) in 43.6% cases. Prolonged mixed type hypoxia and persistence of impaired tissue perfusion, shown by rheovasography, play an important role in the mechanisms of development of complications. Early onset (6-8, 10-12 h after the beginning of treatment) and long standing of disseminated intravascular coagulation (DIC) contributes to the pathogenesis of polyorgan failure. A protocol of pathogenetically validated measures for the prevention and treatment of DIC is presented as one of approaches to the prevention and treatment of polyorgan failure.

Language: ru