Citation

Halasz MF, Formanek J, Marrazzi AS. Science 1969; 164(879): 569-571.

Copyright

(Copyright © 1969, American Association for the Advancement of Science)

DOI

unavailable

PMID

4305078

Abstract

Study of the competition between hallucinogens and tranquilizers at cerebral synapses and on behavior in various species of animals indicates a continuum of effects from protection to dominance of tranquilizer toxicity as the dose of tranquilizer increases. Data on cat and monkey behavior, supplementing that on the rat, show that it is possible to arrive at a tranquilizer dose that can aggravate instead of protect, in accord with the competitive inhibitory nature of the interaction of hallucinogen and tranquilizer.

Language: en