Citation

Nezelof S, Taccoen Y, Corcos M, Girardon N, Perez-Diaz F, Bizouard P, Venisse JL, Halfon O, Loas G, Lang F, Flament M, Jeammet P. Ann. Med. Interne (Paris) 2001; 152(Suppl 3): IS18-25.

Vernacular Title

Consommation de substances psycho-actives dans une population temoin declaree non

Affiliation

Service de Psychiatrie et Psychologie Médicale, CHU Saint-Jacques, 25030 Besançon Cedex.

Copyright

(Copyright © 2001, Masson Editeur)

DOI

unavailable

PMID

11435991

Abstract

AIMS: This study, conducted within the framework of a broader research program of the INSERM 494013 Dependence Network, was designed to estimate illicit drug use and tobacco smoking in a declared non-addicted sample and to determine whether illicit drug users differ from non-users in terms of comorbidity. METHODS: The study was conducted in an "all and sundry" sample of subjects. Patterns of drug use and comorbid factors (psychiatric disorders, suicide attempts, repeated accidents, social inadaptation) were assessed using a semi-structured interview (heteroevaluation, MINI DSM IV interview, Gröningen). RESULTS: Among 860 subjects, 107 (12.4%) used illicit drugs and 26 of these 107 (24.3%) were dependent users or abusers. Specific analysis of non-dependent non-abuser subjects who had used illicit drugs (70 occasional and 11 regular users) showed a higher rate of use in younger subjects (12.7% in the 15-24 year group, 5.7% in the 24-49 year group) and men. Except for repeated accidents (OR=5.5 [1.6-18.5]), comorbid disorders were not more frequent in non-users than in users. CONCLUSION: Besides use for recreational purposes, the rate of use of illicit drugs with abuse or dependence was high in our non-clinical sample. Although no specific comorbid psychiatric disorders were identified among non-dependent non-abuser subjects who had used illicit drugs, the frequency of repeated accidents evidenced the ill-fated side effects of illicit drugs and/or the specific biopsychological vulnerability of these subjects. This highlights the importance of not neglecting drug abuse.

Language: fr