Citation

Cao L, Li T, Xu K, Liu X. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2001; 18(3): 195-197.

Affiliation

Department of Psychiatry, the First Affiliated Hospital, West China University of Medical Sciences, Chengdu, Sichuan 610041 P. R. China. caoliping@hotmail.com

Copyright

(Copyright © 2001, Sichuan University)

DOI

unavailable

PMID

11402448

Abstract

OBJECTIVE: To examine the relationship of attempted suicide with A-1438G and T102C polymorphisms of 5-HT2A receptor gene. METHODS: Genotypes and allele frequencies of A-1438G and T102C polymorphisms of 5-HT2A receptor gene in 149 attempted suicides and 190 normal controls were examined by polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP). RESULTS: No differences in genotypes and allele frequencies of A-1438G and T102C polymorphisms of 5-HT2A receptor gene were observed between attempted suicides and the controls. However, an association between male attempted suicides and genotype(GG) of A-1438G polymorphism was found. CONCLUSION: These results suggested that liability to suicide behavior might be associated with A-1438G polymorpyhism of 5-HT2A receptor gene in male subjects.

Language: zh