Citation

Muhm M, Stimpfl T, Malzer R, Mortinger H, Binder RL, Vycudilik W, Berzlanovich A, Bauer G, Laggner AN. J. Forensic Sci. 1996; 41(6): 1077-1079.

Affiliation

Emergency Department, University of Vienna.

Copyright

(Copyright © 1996, American Society for Testing and Materials, Publisher John Wiley and Sons)

DOI

unavailable

PMID

8914299

Abstract

Suicidal overdose of chloroquine is rare. We present a 14-year-old girl who was admitted to our Emergency Department after intentional ingestion of 7.5 g of chloroquine base followed by cardiac and respiratory arrest. Despite early mechanical ventilation, cardiac support, and treatment with high doses of diazepam, the patient died. Laboratory investigation indicated disseminated intravascular coagulation confirmed by petechial hemorrhages in the leptomeninges at autopsy, a finding that has not previously been described. Postmortem tissue analysis demonstrated early drug distribution to the medulla oblongata and cerebellum.

Language: en