Citation

Tester DJ, McCormack J, Ackerman MJ. Am. J. Cardiol. 2004; 93(6): 788-791.

Affiliation

Departments of Medicine, Pediatrics, and Molecular Pharmacology, Divisions of Cardiovascular Diseases and Pediatric Cardiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

Copyright

(Copyright © 2004, Elsevier Publishing)

DOI

10.1016/j.amjcard.2003.11.061

PMID

15019897

Abstract

We demonstrate how genetic testing enabled a molecular prenatal diagnosis of congenital long QT syndrome in a 20-week fetus presenting with fetal bradycardia in the setting of maternal beta-blocker therapy. Before prenatal testing, strategic genotyping, based on a family history of a near drowning, was performed on a 3-generation family with clinically diagnosed long QT syndrome in which the affected mother was pregnant.

Language: en